APA
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Maclean, M., Kureshi, N., Shankar, J., Stewart, S., & Christie, S. D. (2021). Modic changes and clinical outcomes in patients undergoing lumbar surgery for disc herniation. Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques.
Chicago/Turabian
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Maclean, M., N. Kureshi, J. Shankar, S. Stewart, and SD Christie. “Modic Changes and Clinical Outcomes in Patients Undergoing Lumbar Surgery for Disc Herniation.” Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques (2021).
MLA
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Maclean, M., et al. “Modic Changes and Clinical Outcomes in Patients Undergoing Lumbar Surgery for Disc Herniation.” Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques, 2021.
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@article{m2021a,
title = {Modic changes and clinical outcomes in patients undergoing lumbar surgery for disc herniation},
year = {2021},
journal = {Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques},
author = {Maclean, M. and Kureshi, N. and Shankar, J. and Stewart, S. and Christie, SD}
}
Background: Lumbar disc herniation (LDH) is a risk factor for Modic change (MC) development on spinal MRI. MC has been associated with worse pre- and post-operative pain, disability, and health-related quality of life (HRQoL). We examined the relationship between pre-operative MC and post-operative assessment scores for patients receiving discectomy (LD) or transforaminal interbody fusion (TLIF) for LDH. Methods: We reviewed 285 primary single-level surgeries. Pre-operative and 12-month post-operative assessment scores: Visual Analog Scale Leg-Pain (VAS-LP), Oswestry Disability Index (ODI), and Short-Form-36 Physical Component Summary (SF-36-PCS). MC subgroup on pre-operative MRI was recorded by a single neuroradiologist. Results: 179 patients were included. The sample prevalence of MC on pre-operative MRI was 62%; MC2 was most common (35%). No differences in pre-operative scores were identified, regardless of present or absent MC. For the overall cohort, improvement in assessment scores were observed: SF-36 improved an average of 8.2 points (95% CI: [5.8, 10.7]), ODI by 11.3 points (95% CI: [8.7, 14.0]), and VAS by 2.8 points (95% CI: [2.1, 3.5]). In nearly all cases, MCID values were met. Conclusions: Clinically significant improvement in post-operative pain, disability, and HRQoL was observed for both procedures. Modic change on pre-operative MRI was not associated with worse clinical assessment scores.